Natural Mosquito-Pathogen Hybrid IgG4 Antibodies in Vector-Borne Diseases: A Hypothesis
نویسندگان
چکیده
منابع مشابه
Natural Mosquito-Pathogen Hybrid IgG4 Antibodies in Vector-Borne Diseases: A Hypothesis
Chronic exposure to antigens may favor the production of IgG4 antibodies over other antibody types. Recent studies have shown that up to a 30% of normal human IgG4 is bi-specific and is able to recognize two antigens of different nature. A requirement for this specificity is the presence of both eliciting antigens in the same time and at the same place where the immune response is induced. Duri...
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1 Section of Infectious Diseases, Yale University School of Medicine, New Haven, CT 06512, USA 2Department of Biological Sciences, University of Southern Mississippi, Hattiesburg, MS 39406, USA 3Department of Basic Medical Sciences, School of Medicine, Tsinghua University, Beijing 100084, China 4 Institute of Biology and Medical Sciences, Jiangsu Key Laboratory of Infection and Immunity, Soocho...
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ژورنال
عنوان ژورنال: Frontiers in Immunology
سال: 2016
ISSN: 1664-3224
DOI: 10.3389/fimmu.2016.00380